Pharmaceutical and Toxicological Properties of Engineered Nanomaterials for Drug Delivery
نویسندگان
چکیده
منابع مشابه
Immunological properties of engineered nanomaterials.
Most research on the toxicology of nanomaterials has focused on the effects of nanoparticles that enter the body accidentally. There has been much less research on the toxicology of nanoparticles that are used for biomedical applications, such as drug delivery or imaging, in which the nanoparticles are deliberately placed in the body. Moreover, there are no harmonized standards for assessing th...
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Poloxamines (Tetronic) are X-shaped amphiphilic block copolymers formed by four arms of poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) blocks bonded to a central ethylenediamine moiety. Such a structure confers multi-responsive behaviour, namely temperature and pH-sensitiveness. At relatively low concentrations but above the critical micellar concentration (CMC), poloxamines generate poly...
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ژورنال
عنوان ژورنال: Annual Review of Pharmacology and Toxicology
سال: 2014
ISSN: 0362-1642,1545-4304
DOI: 10.1146/annurev-pharmtox-010611-134615